A study led by researchers from the University of Plymouth and University Hospitals Plymouth NHS Trust has investigated the link between brain abscesses and oral bacteria.
Although this type of abscess is uncommon, it can significantly increase mortality and morbidity.
The study examined the records of 87 hospitalised patients with brain abscesses. Through analysing samples of the abscesses and peripheral cultures, they collected microbiological data.
Researchers found that the 52 patients who had no diagnosable cause for their abscess, were three times more likely to have oral bacteria present.
In particular, the team noted the presence of Streptococcus anginosus. This bacteria can lead to “pharyngitis, bacteremia, and infections in internal organs such as the brain, lung, and liver. This bacteria is often found in dental abscesses.”
Speaking to EurekaAlert!, Dr Holly Roy, the studies lead author said, “While many potential causes of brain abscesses are recognised, the origin of infection often remains clinically unidentified. However, it was still surprising to frequently find orally occurring bacteria in brain abscesses of unexplained origin. It highlights the importance of using more sensitive techniques to assess the oral cavity as a potential bacterial source in brain abscess patients. It also highlights the importance of improving dental care and oral hygiene more generally.”
Ongoing research is taking place within the university’s Oral Microbiome Research Group to examine the link between oral microbes and a variety of cardiovascular and neurological conditions.