Yan Gao is a masters student from the School of Stomatology at Capital Medical University in Beijing, where she has studied dentistry for five years and orthodontics for one year. Yan’s visit is for six months and she will be working with internationally-renowned stem cell researcher, Bing Hu.
Their research project will focus on better understanding stem cells and their role in craniofacial tissue and bone regeneration – how they are activated, can prevent damage and accelerate wound healing.
There are two targets for the research: the first is to develop a way to accelerate new bone and tooth ligament formation during tooth movement due to orthodontic treatment (especially in children), to reduce the current significant length of clinical treatment and cost.
The second is to understand the mechanism of bone development deformity in children with Crouzon Syndrome (CS), a rare genetic disorder where soft bones in young children’s skulls fuse prematurely (usually there is flexibility to allow for the head and the structures and functions within it to grow).
Treatment of CS patients is long, painful and requires multiple plastic surgery and orthodontic operations and therapies. Targeting stem cells in the bone may hold the key to accelerated healing, reducing the painful period for the patient. Very few research groups are working in this area. The team is collaborating with Pauws Erwin from the UCL Institute of Child Health for the project.
Yan said, “It’s great being here in Plymouth and very exciting to be the first student from China to visit as part of these new arrangements. At home, I am a research clinician with 60 child and adult patients. While in Plymouth, I am looking forward to working with Bing and his colleagues and to learning new technology. Everyone here is so friendly and always offering help in the lab.
“I hope that my experiences here will encourage more of my colleagues at Capital Medical University, and the other institutions in China that are part of the partnership, to come to Plymouth and build on our collaboration.”
Bing Hu, associate professor in oral and dental health research at Plymouth University Peninsula School of Dentistry, commented, “I have collaborated with Yan’s supervisor for some years and we have joint work under submission for publication. Yan’s arrival is very exciting, because it marks the practical start to a partnership with immense potential for research and education.”
Professor Christopher Tredwin, head of Plymouth University Peninsula School of Dentistry, said, “We are delighted to welcome Yan to our team and we are looking forward to working with her over the coming months. Our collaboration with the School of Stomatology at Capital Medical University is one of many we have forged with institutions around the world, from China to Canada, the USA, Switzerland, Denmark, New Zealand, Finland, the Czech Republic, Hungary, Turkey, Croatia, Syria, Sweden, Poland, Spain, France, Germany, The Netherlands and Belgium.”
The agreement with the School of Stomatology at Capital Medical University is one of four with institutions in China. The others are with Shen Yang Hospital of Stomatology; the School of Stomatology, Shandong University; and the Second Hospital (School of Clinical Medicine), also Shandong University.